Unduh sebagai doc, pdf, txt atau baca online dari scribd. There is evidence that the size of primary tumor, infiltration of. Terletak didalam scrotum dengan axis panjang pada sumbu vertikal dan biasanya testis kiri terletak lebih rendah dibanding kanan. Three types will be considered, namely, leydig cell tumors, sertoli cell tumors, and gonadoblastomas. Scribd is the worlds largest social reading and publishing site. U, mars surgery departement faculty of medicine sriwijaya university rsup dr. For a scrotal mass it is difficult to distinguish a benign or malignant etiology, in addition to the origin whether from testis or epididymis. Leydig cell tumor is the most common stromal tumor of the testis, followed by sertoli cell tumors. Testis diliputi oleh tunika albuginea pada 23 anterior kecuali pada sisi dorsal dimana terdapat. Ultrasound images of the scrotum showed an eccentric, predominantly hypoechoic vascular mass in the posterior aspect of the right testis measuring 2. Traditionally limbic encephalitis was considered in the context of a tumour paraneoplastic di sease with onconeuronal antibodies against in tracellular proteins. Leydig cell carcinoma is relatively refractory to radiotherapy and chemotherapy, and median survival of patients with metastatic disease is less than 2.
Around half of all cases occur in men aged under 35 but testicular cancer rarely occurs before puberty. The adult type of granulosa cell tumor is extremely rare in the testis 46 cases have been described to date table 31. Tumor testis biasanya berkembang selama masa pubertas, walaupun beberapa penelitian menyatakan tumor berkembang sebelum usia 10 tahun. Ratarata 10% dari tumor testis berasal dari undesensus testis. Anatomi dan fisiologi testis merupakan sepasang struktur organ yang berbentuk oval dengan ukuran 4x2,5x2,5cm dan berat kurang lebih 20g. Leydig cell tumor of the testis radiology reference article. However, the incidence of testicular tumors in children is increasing, and associated morbidity has doubled during the last 40 years 4, 5. Oncotesticular sperm extraction oncotese for bilateral.
Tumor testis free download as powerpoint presentation. Well circumscribed, slow growing, non invasive, non metastatic. Stefanie angeline 04084821719171 siti evi marissa 04054821719116 supervised by. Initial stages of malignant cancer may typically show benign growth. Start studying medical terminology ch9 male reproductive system. Erasmus, 2006 netherlands pmid 17158533 controversies in the management of clinical stage i testis cancer. In nonneoplastic testicular tissue, the seminiferous tubules showed sertoli cells with complete spermatogenesis, hematoxylineosin stain x10 b. In terms of occurrence patterns, oncotese in testicular cancer can be categorized into three types. Germ cell tumors of the testis tumors of the testis. Primary bilateral tumors of the testis may happen synchronously or asynchronously but tend to be of the same histologic type. Its imaging appearance on ultrasound and mri is nonspecific, but clinically it is associated with serum hormonal imbalance. Adult granulosa cell tumor of the testis masquerading as. According to ajcc, tumors confined to testis without lymph node involvement are stated as stage i.
In broad terms, testicular cancer is staged as follows. The tumor characteristics may include subsite, size of tumor, extension of the tumor, lymph nodes positive, distant metastases, and histologic type. Oncotesticular sperm extraction oncotese from a single. The remaining 60 patients were treated with high inguinal orchiectomy. In the prepubertal testis tumor registry, 11% of patients had a hydrocele at presentation, which may have been secondary to the tumor or coincidental. Malignant germ cell tumor composed of primitive epithelial tumor cells recapitulating early stages of embryonic development. While most adult gcts are benign, those that present with distant metastases manifest a grave prognosis. A leydig cell tumor of the testis is an uncommon testicular neoplasm. Microscopically, the uninvolved parenchyma of the right testis showed fig. Most common patterns are microfollicular and diffuse other patterns trabecular. Tumor testis merupakan keganasan terbanyak pada pria berusia diantara 1535 tahun dan merupakan 12% dari semua neoplasma pada pria. Download as doc, pdf, txt or read online from scribd. Testicular sex cord stromal tumors include leydig cell tumors, sertoli cell tumors, and granulosa cell tumors. Learn vocabulary, terms, and more with flashcards, games, and other study tools.
A malignant leydig cell tumor of the testis springerlink. Adult type granulosa cell tumor of the testis with a. Leydig cell tumor of the testis radiology reference. Ppt referat torsio testis free download as powerpoint presentation. Jika tumor testis sekunder disingkirkan maka insiden tumor testis primer bilateral 1 2,8 % dari seluruh kasus tumor sel germinal testis. The latter mostly concerned infants and followed a benign course.
Figenshau 1 division of urologic surgery, washington university school of medicine, st. Testicular cancer is categorized as being in one of three stages which have subclassifications. Testicular tumor undescended testis testicular torsion granulosa cell tumor leydig cell tumor these keywords were added by machine and not by the authors. Sertoli cell tumors of the testis are uncommon sex cord stromal tumors. The tumor was surrounded by an incomplete, dense lamellar area. Out of these, 30 cases were of the adult type, while the remainder 50 cases were of the juvenile type. Introductio testicular conclusion n torsion introduction. Nov 11, 2008 epididymal inflammatory myofibroblastic tumor, also known by various other synonyms is a rare benign disease. The patient characteristics are age, race, and sex. Nongerm cell tumors of the testis tumors of the testis. Ileri evre testis tumorunde, international germ cell cancer.
Education exhibits 665 mr imaging of scrotal tumors and. The presence of a hydrocele may delay the diagnosis of a testis tumor, and an ultrasound scan should be considered for any boy with a hydrocele in which the testis cannot be palpated. A 40yearold man was referred to our hospital with gynecomastia and painless swelling of the right scrotum. The incidence testicular of torsion in males younger urological torsion is a emergency. Current experience on sertoli cell tumor of the testis sctt is insufficient to prognosticate the clinical behavior of the primary tumor on the long. The most common type is germ cell tumors which are divided into seminomas and nonseminomas. It is the most common cancer in men aged 1544 years. Mixed germ cell tumour of infantile testis showing. The incidence testicular of torsion in males younger urological torsion is a. Epididymal inflammatory myofibroblastic tumor, also known by various other synonyms is a rare benign disease. Pathology outlines mixed unclassified sex cord stromal. The testis is surrounded by the tunica albuginea, which has low t1 and t2 signal intensity.
Approximately 56% of all testis tumors are nongerm cell tumors of the testis. Testicular cancer is a cancer that arises from a testicle testis. Seminoma is the most common germ cell tumor in bilateral primary testicular tumors, while malignant lymphoma is the most common bilateral tumor of the testis. Guidelines for the diagnosis and staging of testicular cancer. Not well organized, irregularly shaped, fast growing, infiltrative growth, metastatic. Primary neuroendocrine tumor of the testis article pdf available in urology annals 62.
Abstract a rare case of malignant sertoli cell tumor of the testis occurred in which the diagnosis was initially suggested on fine needle aspiration cytology. Insiden tumor testis pada populasi umum adalah satu dari 100. Tumor limited to testis and epididymis without vascularlymphatic invasion. Metastatic leydig cell tumor of the testis report of three. The size of the tumor in the testis is irrelevant to staging. Dec 29, 2014 more recently, testis sparing surgery has been suggested as a safe and efficacious choice for patients with a testicular tumor of its diameter less than 2 cm. Treatments for aggressive gcts are not well established. Metastatic leydig cell carcinomas account for less than 0. In the current study, only one case had a tumor that was less than 2 cm. Histologically, reinkes crystals and capsular invasion by tumor cells were found. There are about 2,000 new cases in the uk each year. Clinical presentation and management anandmohapatra, 1 aaronm. Kepaniteraan klinik tht rumah sakit umum daerah karawang fakultas kedokteran universitas trisakti periode 8 oktober 9 november 2012 lembar pengesahan 1 nama. As a benign neoplasm, radical orchiectomy is sufficient for treatment.
The majority of patients with prepubertal testis tumors present with stage i disease80% in the prepubertal testis tumor registry. Tumor ini mempunyai derajat keganasan tinggi, tetapi dapat sembuh bila diberi penanganan adekuat. The mediastinum testis has signal intensity similar to that of the testis on t1weighted images and is lower in signal intensity than the testis on t2weighted images. The rete testis radiates from the mediastinum testis to the surface of the tunica. Bie van wiele tielt heeft bij routine klinisch onderzoek bij een hond testis knobbels gepalpeerd. Testicular yolk sac tumors account for 70% to 80% of prepubertal malignant testicular tumors and are the most common.
In 2009, it was found in 2570 cases of malignant primary bone tumor, and 1470 of them died because this disease. They are less common than leydig cell tumors of the testis. Intratubular germ cell neoplasia carcinoma in situ in situ, intraepithelial, noninvasive. Cancer survival among adults us seer program, 19882001. Other types include sexcord stromal tumors and lymphomas. Options that have been employed in previous cases include retroperitoneal lymph node dissection rplnd. Epididimitis atau pembengkakan epididimis lain, hidrokel, atau tumor testis tidak memberikan sensasi khas itu. Testicular cancer urology associates of northeast florida. Testicular cancer is the most common malignancy that develops in men between the ages of 20. A rare case of primary carcinoid tumor in otherwise mature teratoma of the testis which occurred in a 70yearold male is reported.
Tumor may invade tunica albuginea but not tunica vaginalis. Alphafetoprotein afp is a tumor marker that is elevated in 6070% of patients with hepatocellular carcinoma. Leydig cell tumors see the image below are derived from normal leydig cells that produce testosterone and are located in the interstitium of the testis. Final diagnosis, the tumor was a malignant leydig cell tumor of the testis.
Yolk sac tumor has also been known over the years as endodermal sinus tumor, juvenile embryonal carcinoma, embryonal adenocarcinoma, distinctive adenocarcinoma of the infant testis, testicular adenocarcinoma with clear cells, and orchioblastoma,14,15,16,17,18 current evidence has. Referat primery bone tumors benign tumor neoplasms. This process is experimental and the keywords may be updated as the learning algorithm improves. Diagnosis is typically based on a physical exam, ultrasound, and blood tests. Myoid gonadal stromal tumor of the testis is an uncommon spindle cell tumor hypothesized to arise from peritubular myoid cells or intertubular primitive mesenchymal cells. Granulosa cell tumor gst is a sexcordstromal neoplasm of the gonads, more commonly arising in the ovaries, while approximately 80 cases have been reported in the testes.
Due to the rarity of these tumors, exact etiology, pathogenesis, prognostic factors and best treatment approach are not well known. Risk factors include an undescended testis, family history of the disease, and previous history of testicular cancer. Alive dead alive or dead without tumor total from tumor other cause total per cent total 51 24 27 24 3 27 52. Unduh sebagai pptx, pdf, txt atau baca online dari scribd.
Radiation oncologytestisoverview wikibooks, open books. Detection of occult primary tumors in patients with metastatic germ cell tumors17 or unex. Myoid gonadal stromal tumor american journal of clinical. Testicular tumors are uncommon in children, comprising approximately 1% to 2% of all pediatric malignancies 14. Tumor testis berasal dari sel germinal atau jaringan stroma testis. Sertoli cell tumor of the testis sertoli cell testicular. The most common presentation is a scrotal mass of variable duration. Tumor primer testis bilateral dapat terjadi secara berbarengan ataupun tidak, tetapi cenderung memiliki kesamaan jenis histilogisnya. Granulosa cell tumor of testis is a rare tumor accounting for less than 4% of adult testicular tumors though they account for nearly 30% of childhood testicular tumors. Whereas granulosa cell tumors are typical for the ovaries. May 10, 2017 testicular sex cord stromal tumors include leydig cell tumors, sertoli cell tumors, and granulosa cell tumors. Diagnosis alphafetoprotein afp alphafetoprotein levels may be assessed by a blood test. Neonatal testicular tumors are rare and should be considered in the differential diagnosis of newborn scrotal masses.
Germ cell tumors of the testis tumors of the testis health. We report a case of a newborn with a prenatal diagnosis of scrotal mass. After surgery, the histological diagnosis was juvenile granulosa cell tumor. Louis, mo, usa department of pathology, washington university school of medicine, st. Granulosa cell tumors gcts of the testis are rare sex cordstromal tumors that are present in both juvenile and adult subtypes. Epidemiology may present in both pediatric and adult males, depending on the histologic subtype. Case report metastatic granulosa cell tumor of the testis. Tumors of the testis, adnexa, spermatic cord, and scrotum. Due to the rarity of these tumors, exact etiology, pathogenesis, prognostic factors. Options that have been employed in previous cases include retroperitoneal lymph node dissection.
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